Mastering Metabolism for Lifelong Health | Key Takeaways from Dr. Monisha Bhanote on the Whole Life Action Hour

Dr. Monisha Bhanote was recently featured on the Whole Life Action Hour with Ocean Robbins, where she shared essential insights on how to cultivate resilient, balanced, and healthy metabolism through science-backed lifestyle choices. As a quintuple board-certified physician and founder of Wellkulå, Dr. Bhanote brings a unique perspective that integrates conventional medicine with integrative, lifestyle-focused strategies to optimize energy, vitality, and long-term health. This conversation is a must-listen for anyone seeking sustainable approaches to metabolic health without relying solely on medications.

You can listen to the full episode here or in your favorite podcast player.

1. The Foundation of Metabolic Mastery

Dr. Bhanote defines “metabolic mastery” as the body’s ability to efficiently convert nutrients and oxygen into energy while maintaining blood sugar balance and managing inflammation. She explains that a well-functioning metabolism affects every aspect of health — from mental clarity and digestion to weight management and stress resilience. At the cellular level, this hinges on the health of our mitochondria, the energy-producing powerhouses within our cells. Dr. Bhanote highlights the significant impact of nutrition, contrasting the Standard American Diet (SAD), rich in ultra-processed foods, with a whole-food, plant-based diet that provides the critical nutrients needed to support mitochondrial function, reduce inflammation, and regulate blood sugar. Her message is clear: most people are overfed yet undernourished, and metabolic dysfunction is often a result of chronic nutrient gaps, poor dietary patterns, and unmanaged stress.

2. The Microbiome and Metabolic Health

Dr. Bhanote emphasizes the gut microbiome as a “metabolic command center.” A diverse and well-nourished microbiome is essential for digestion, blood sugar regulation, fat storage, and even mood. She explains how prebiotic fibers and polyphenols found in foods like oats, berries, garlic, and green tea fuel beneficial gut bacteria. These microbes, in turn, produce short-chain fatty acids (SCFAs) like butyrate, which enhance mitochondrial health, regulate blood sugar, reduce inflammation, and even stimulate natural GLP-1 production—a hormone crucial for appetite regulation and metabolic control. While GLP-1 medications like Ozempic are popular, Dr. Bhanote advocates for supporting the body’s natural processes through targeted nutrition and lifestyle choices, offering a safer, more sustainable path to metabolic health.

3. Stress, Vagus Nerve Activation, and Metabolic Resilience

Chronic stress disrupts metabolism by elevating cortisol, raising blood sugar, and promoting fat storage. Dr. Bhanote explains how nervous system regulation is key to metabolic health. She recommends simple vagus nerve-stimulating practices like humming, chanting, deep breathing, and cold exposure to shift the body into a parasympathetic state, where digestion and repair occur more efficiently. These practices aren’t just about feeling calmer — they directly improve digestion, lower inflammation, and stabilize blood sugar. In addition, she highlights the importance of aligning lifestyle habits with circadian rhythms—morning sunlight exposure, consistent meal timing, and early bedtimes—to further support metabolism, energy, and longevity.

Listen to the Full Episode

Dr. Monisha Bhanote’s guidance offers a refreshing, root-cause perspective on metabolic health. By prioritizing movement, nutrient-dense plant-based foods, gut health, and stress resilience, you can support your metabolism naturally—without relying on medications.

Tune in to the full episode here on your favorite podcast platform or visit Dr. Bhanote’s website for more resources on plant-powered living and integrative health.

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About the Author

Monisha Bhanote, MD, FCAP, ABOIM, is one of the few quintuple board-certified physicians in the nation. She combines ancient wisdom with mind-body science to naturally bio-hack the human body through her expertise as a cytopathologist, functional culinary medicine specialist, and integrative lifestyle medicine doctor. Known as the Wellbeing Doctor, Dr. Bhanote has diagnosed over one million cancer cases, provides health programs at DrBhanote.com, and leads wellness workshops and retreats worldwide. Featured in Shape, Reader’s Digest, and Martha Stewart Living, Dr. Bhanote serves on several clinical advisory boards and is a go-to health and wellness expert for Healthline, Psych Central, and Medical News Today.

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